First let me say that if I-80 were the first highway I had to do, I would never have started this project. This road has more intersections in the middle of nowhere (thank you IL) and whacky connections with other roads (including being joined with I-90 for most of IN and OH) than any 5 other Interstates.
It also has I-180 in Cheyenne, which is an interstate with traffic lights (thanks to Mark Bozanich for pointing this out to me). I have no idea what is up with that.
It can be argued that I-80 goes all of the way to the George Washington Bridge, but I think that's just silly. :)